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Composites of silica with immobilized cholinesterase incorporated into polymeric shell
Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the pol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385111/ https://www.ncbi.nlm.nih.gov/pubmed/25852378 http://dx.doi.org/10.1186/s11671-015-0808-4 |
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author | Payentko, Victoriya Matkovsky, Alexander Matrunchik, Yulia |
author_facet | Payentko, Victoriya Matkovsky, Alexander Matrunchik, Yulia |
author_sort | Payentko, Victoriya |
collection | PubMed |
description | Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the polysiloxane matrixes during sol-gel synthesis. Evaluation of the cholinesterase activity has been fulfilled through the imitation of the acetylcholine chloride decomposition reaction. Values of activity for cholinesterase nanocomposites demonstrated in this work are higher than those for the native cholinesterase. The higher activity of cholinesterase contained in nanocomposites was found for those prepared using highly dispersed silica. |
format | Online Article Text |
id | pubmed-4385111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-43851112015-04-07 Composites of silica with immobilized cholinesterase incorporated into polymeric shell Payentko, Victoriya Matkovsky, Alexander Matrunchik, Yulia Nanoscale Res Lett Nano Express Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the polysiloxane matrixes during sol-gel synthesis. Evaluation of the cholinesterase activity has been fulfilled through the imitation of the acetylcholine chloride decomposition reaction. Values of activity for cholinesterase nanocomposites demonstrated in this work are higher than those for the native cholinesterase. The higher activity of cholinesterase contained in nanocomposites was found for those prepared using highly dispersed silica. Springer US 2015-02-27 /pmc/articles/PMC4385111/ /pubmed/25852378 http://dx.doi.org/10.1186/s11671-015-0808-4 Text en © Payentko et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Nano Express Payentko, Victoriya Matkovsky, Alexander Matrunchik, Yulia Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title | Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title_full | Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title_fullStr | Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title_full_unstemmed | Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title_short | Composites of silica with immobilized cholinesterase incorporated into polymeric shell |
title_sort | composites of silica with immobilized cholinesterase incorporated into polymeric shell |
topic | Nano Express |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385111/ https://www.ncbi.nlm.nih.gov/pubmed/25852378 http://dx.doi.org/10.1186/s11671-015-0808-4 |
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