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Composites of silica with immobilized cholinesterase incorporated into polymeric shell

Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the pol...

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Detalles Bibliográficos
Autores principales: Payentko, Victoriya, Matkovsky, Alexander, Matrunchik, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385111/
https://www.ncbi.nlm.nih.gov/pubmed/25852378
http://dx.doi.org/10.1186/s11671-015-0808-4
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author Payentko, Victoriya
Matkovsky, Alexander
Matrunchik, Yulia
author_facet Payentko, Victoriya
Matkovsky, Alexander
Matrunchik, Yulia
author_sort Payentko, Victoriya
collection PubMed
description Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the polysiloxane matrixes during sol-gel synthesis. Evaluation of the cholinesterase activity has been fulfilled through the imitation of the acetylcholine chloride decomposition reaction. Values of activity for cholinesterase nanocomposites demonstrated in this work are higher than those for the native cholinesterase. The higher activity of cholinesterase contained in nanocomposites was found for those prepared using highly dispersed silica.
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spelling pubmed-43851112015-04-07 Composites of silica with immobilized cholinesterase incorporated into polymeric shell Payentko, Victoriya Matkovsky, Alexander Matrunchik, Yulia Nanoscale Res Lett Nano Express Synthetic approaches for new nanocomposite materials with relatively high cholinesterase activity have been developed. The peculiarity of the formation of such systems is the introduction of cholinesterase into polymer with subsequent incorporation on the ready-made silica particles and into the polysiloxane matrixes during sol-gel synthesis. Evaluation of the cholinesterase activity has been fulfilled through the imitation of the acetylcholine chloride decomposition reaction. Values of activity for cholinesterase nanocomposites demonstrated in this work are higher than those for the native cholinesterase. The higher activity of cholinesterase contained in nanocomposites was found for those prepared using highly dispersed silica. Springer US 2015-02-27 /pmc/articles/PMC4385111/ /pubmed/25852378 http://dx.doi.org/10.1186/s11671-015-0808-4 Text en © Payentko et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Nano Express
Payentko, Victoriya
Matkovsky, Alexander
Matrunchik, Yulia
Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title_full Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title_fullStr Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title_full_unstemmed Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title_short Composites of silica with immobilized cholinesterase incorporated into polymeric shell
title_sort composites of silica with immobilized cholinesterase incorporated into polymeric shell
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385111/
https://www.ncbi.nlm.nih.gov/pubmed/25852378
http://dx.doi.org/10.1186/s11671-015-0808-4
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