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Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification st...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385601/ https://www.ncbi.nlm.nih.gov/pubmed/25873991 http://dx.doi.org/10.1155/2015/941680 |
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author | Zhao, Mingzhu Chen, Lei Bian, Linjie Zhang, Jianhua Yao, Chunyan Zhang, Jianwei |
author_facet | Zhao, Mingzhu Chen, Lei Bian, Linjie Zhang, Jianhua Yao, Chunyan Zhang, Jianwei |
author_sort | Zhao, Mingzhu |
collection | PubMed |
description | Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification standard and expert diagnostic experience, expressive descriptors are extracted according to morphology, color, and texture features of cervical scales epithelial cells. Further, quantificational descriptors related to cytopathology are derived as well, including morphological difference degree, cell hyperkeratosis, and deeply stained degree. The relationship between quantified value and pathological feature can be established by these descriptors. Finally, an effective method is proposed for detecting abnormal cells based on feature quantification. Integrated with clinical experience, the method can realize fast abnormal cell detection and preliminary cell classification. |
format | Online Article Text |
id | pubmed-4385601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43856012015-04-13 Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells Zhao, Mingzhu Chen, Lei Bian, Linjie Zhang, Jianhua Yao, Chunyan Zhang, Jianwei Comput Math Methods Med Research Article Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification standard and expert diagnostic experience, expressive descriptors are extracted according to morphology, color, and texture features of cervical scales epithelial cells. Further, quantificational descriptors related to cytopathology are derived as well, including morphological difference degree, cell hyperkeratosis, and deeply stained degree. The relationship between quantified value and pathological feature can be established by these descriptors. Finally, an effective method is proposed for detecting abnormal cells based on feature quantification. Integrated with clinical experience, the method can realize fast abnormal cell detection and preliminary cell classification. Hindawi Publishing Corporation 2015 2015-03-22 /pmc/articles/PMC4385601/ /pubmed/25873991 http://dx.doi.org/10.1155/2015/941680 Text en Copyright © 2015 Mingzhu Zhao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zhao, Mingzhu Chen, Lei Bian, Linjie Zhang, Jianhua Yao, Chunyan Zhang, Jianwei Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title | Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title_full | Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title_fullStr | Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title_full_unstemmed | Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title_short | Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells |
title_sort | feature quantification and abnormal detection on cervical squamous epithelial cells |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385601/ https://www.ncbi.nlm.nih.gov/pubmed/25873991 http://dx.doi.org/10.1155/2015/941680 |
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