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Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells

Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification st...

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Detalles Bibliográficos
Autores principales: Zhao, Mingzhu, Chen, Lei, Bian, Linjie, Zhang, Jianhua, Yao, Chunyan, Zhang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385601/
https://www.ncbi.nlm.nih.gov/pubmed/25873991
http://dx.doi.org/10.1155/2015/941680
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author Zhao, Mingzhu
Chen, Lei
Bian, Linjie
Zhang, Jianhua
Yao, Chunyan
Zhang, Jianwei
author_facet Zhao, Mingzhu
Chen, Lei
Bian, Linjie
Zhang, Jianhua
Yao, Chunyan
Zhang, Jianwei
author_sort Zhao, Mingzhu
collection PubMed
description Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification standard and expert diagnostic experience, expressive descriptors are extracted according to morphology, color, and texture features of cervical scales epithelial cells. Further, quantificational descriptors related to cytopathology are derived as well, including morphological difference degree, cell hyperkeratosis, and deeply stained degree. The relationship between quantified value and pathological feature can be established by these descriptors. Finally, an effective method is proposed for detecting abnormal cells based on feature quantification. Integrated with clinical experience, the method can realize fast abnormal cell detection and preliminary cell classification.
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spelling pubmed-43856012015-04-13 Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells Zhao, Mingzhu Chen, Lei Bian, Linjie Zhang, Jianhua Yao, Chunyan Zhang, Jianwei Comput Math Methods Med Research Article Feature analysis and classification detection of abnormal cells from images for pathological analysis are an important issue for the realization of computer assisted disease diagnosis. This paper studies a method for cervical squamous epithelial cells. Based on cervical cytological classification standard and expert diagnostic experience, expressive descriptors are extracted according to morphology, color, and texture features of cervical scales epithelial cells. Further, quantificational descriptors related to cytopathology are derived as well, including morphological difference degree, cell hyperkeratosis, and deeply stained degree. The relationship between quantified value and pathological feature can be established by these descriptors. Finally, an effective method is proposed for detecting abnormal cells based on feature quantification. Integrated with clinical experience, the method can realize fast abnormal cell detection and preliminary cell classification. Hindawi Publishing Corporation 2015 2015-03-22 /pmc/articles/PMC4385601/ /pubmed/25873991 http://dx.doi.org/10.1155/2015/941680 Text en Copyright © 2015 Mingzhu Zhao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhao, Mingzhu
Chen, Lei
Bian, Linjie
Zhang, Jianhua
Yao, Chunyan
Zhang, Jianwei
Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title_full Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title_fullStr Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title_full_unstemmed Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title_short Feature Quantification and Abnormal Detection on Cervical Squamous Epithelial Cells
title_sort feature quantification and abnormal detection on cervical squamous epithelial cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385601/
https://www.ncbi.nlm.nih.gov/pubmed/25873991
http://dx.doi.org/10.1155/2015/941680
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