Cargando…

Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications

Cocaine is used by approximately 1.5 million Americans each month and up to 69% of the cocaine seized contains levamisole. The real incidence of cocaine-levamisole induced neutropenia is unclear but probably underestimated. Associated complications include fever, thrombocytopenia, skin-vasculitis di...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez, Eduardo, Alvi, Raza, Venkatram, Sindhaghatta, Diaz-Fuentes, Gilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385627/
https://www.ncbi.nlm.nih.gov/pubmed/25874134
http://dx.doi.org/10.1155/2015/303098
_version_ 1782365061501681664
author Martinez, Eduardo
Alvi, Raza
Venkatram, Sindhaghatta
Diaz-Fuentes, Gilda
author_facet Martinez, Eduardo
Alvi, Raza
Venkatram, Sindhaghatta
Diaz-Fuentes, Gilda
author_sort Martinez, Eduardo
collection PubMed
description Cocaine is used by approximately 1.5 million Americans each month and up to 69% of the cocaine seized contains levamisole. The real incidence of cocaine-levamisole induced neutropenia is unclear but probably underestimated. Associated complications include fever, thrombocytopenia, skin-vasculitis disorders, and rarely kidney injury. We present a young male, with chronic active cocaine use presenting with recurrent episodes of febrile neutropenia and thrombocytopenia. He underwent extensive work-up and was treated with many antibiotics and we suspect that his neutropenia and thrombocytopenia were caused by recurrent cocaine-levamisole use.
format Online
Article
Text
id pubmed-4385627
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43856272015-04-13 Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications Martinez, Eduardo Alvi, Raza Venkatram, Sindhaghatta Diaz-Fuentes, Gilda Case Rep Crit Care Case Report Cocaine is used by approximately 1.5 million Americans each month and up to 69% of the cocaine seized contains levamisole. The real incidence of cocaine-levamisole induced neutropenia is unclear but probably underestimated. Associated complications include fever, thrombocytopenia, skin-vasculitis disorders, and rarely kidney injury. We present a young male, with chronic active cocaine use presenting with recurrent episodes of febrile neutropenia and thrombocytopenia. He underwent extensive work-up and was treated with many antibiotics and we suspect that his neutropenia and thrombocytopenia were caused by recurrent cocaine-levamisole use. Hindawi Publishing Corporation 2015 2015-03-22 /pmc/articles/PMC4385627/ /pubmed/25874134 http://dx.doi.org/10.1155/2015/303098 Text en Copyright © 2015 Eduardo Martinez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Martinez, Eduardo
Alvi, Raza
Venkatram, Sindhaghatta
Diaz-Fuentes, Gilda
Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title_full Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title_fullStr Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title_full_unstemmed Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title_short Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications
title_sort recurrent febrile neutropenia and thrombocytopenia in a chronic cocaine user: a case of levamisole induced complications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385627/
https://www.ncbi.nlm.nih.gov/pubmed/25874134
http://dx.doi.org/10.1155/2015/303098
work_keys_str_mv AT martinezeduardo recurrentfebrileneutropeniaandthrombocytopeniainachroniccocaineuseracaseoflevamisoleinducedcomplications
AT alviraza recurrentfebrileneutropeniaandthrombocytopeniainachroniccocaineuseracaseoflevamisoleinducedcomplications
AT venkatramsindhaghatta recurrentfebrileneutropeniaandthrombocytopeniainachroniccocaineuseracaseoflevamisoleinducedcomplications
AT diazfuentesgilda recurrentfebrileneutropeniaandthrombocytopeniainachroniccocaineuseracaseoflevamisoleinducedcomplications