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Synthesis of Novel Peptide Dendrimers PDL-GB2 and PDL-G2

Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orient...

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Detalles Bibliográficos
Autores principales: Yunzhu, Lin, Lingling, Weng, Qingrong, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385662/
https://www.ncbi.nlm.nih.gov/pubmed/25874261
http://dx.doi.org/10.1155/2015/907859
Descripción
Sumario:Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. And the structures were identified by (1)HNMR, (13)CNMR, MS, and elemental analysis.