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Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans

Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species...

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Autores principales: Pedrazzi, Vinícius, Leite, Mateus Freire, Tavares, Reisla Cristina, Sato, Sandra, do Nascimento, Glauce Crivelaro, Issa, João Paulo Mardegan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385682/
https://www.ncbi.nlm.nih.gov/pubmed/25874255
http://dx.doi.org/10.1155/2015/712683
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author Pedrazzi, Vinícius
Leite, Mateus Freire
Tavares, Reisla Cristina
Sato, Sandra
do Nascimento, Glauce Crivelaro
Issa, João Paulo Mardegan
author_facet Pedrazzi, Vinícius
Leite, Mateus Freire
Tavares, Reisla Cristina
Sato, Sandra
do Nascimento, Glauce Crivelaro
Issa, João Paulo Mardegan
author_sort Pedrazzi, Vinícius
collection PubMed
description Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (t = 1), there was no difference between products (P = 0.602); that is, subjects in the study had a similar PI after the first use. After one week (t = 2), there was no difference between the four products evaluated (P = 0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care.
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spelling pubmed-43856822015-04-13 Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans Pedrazzi, Vinícius Leite, Mateus Freire Tavares, Reisla Cristina Sato, Sandra do Nascimento, Glauce Crivelaro Issa, João Paulo Mardegan ScientificWorldJournal Clinical Study Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (t = 1), there was no difference between products (P = 0.602); that is, subjects in the study had a similar PI after the first use. After one week (t = 2), there was no difference between the four products evaluated (P = 0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care. Hindawi Publishing Corporation 2015 2015-03-22 /pmc/articles/PMC4385682/ /pubmed/25874255 http://dx.doi.org/10.1155/2015/712683 Text en Copyright © 2015 Vinícius Pedrazzi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Pedrazzi, Vinícius
Leite, Mateus Freire
Tavares, Reisla Cristina
Sato, Sandra
do Nascimento, Glauce Crivelaro
Issa, João Paulo Mardegan
Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_full Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_fullStr Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_full_unstemmed Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_short Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans
title_sort herbal mouthwash containing extracts of baccharis dracunculifolia as agent for the control of biofilm: clinical evaluation in humans
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385682/
https://www.ncbi.nlm.nih.gov/pubmed/25874255
http://dx.doi.org/10.1155/2015/712683
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