Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways

The biochemistry of cancer cells diverges significantly from normal cells as a result of a comprehensive reprogramming of metabolic pathways. A major factor influencing cancer metabolism is hypoxia, which is mediated by HIF1α and HIF2α. HIF1α represents one of the principal regulators of metabolism...

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Detalles Bibliográficos
Autores principales: Valli, Alessandro, Rodriguez, Miguel, Moutsianas, Loukas, Fischer, Roman, Fedele, Vita, Huang, Hong-Lei, Van Stiphout, Ruud, Jones, Dylan, Mccarthy, Michael, Vinaxia, Maria, Igarashi, Kaori, Sato, Maya, Soga, Tomoyoshi, Buffa, Francesca, Mccullagh, James, Yanes, Oscar, Harris, Adrian, Kessler, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385826/
https://www.ncbi.nlm.nih.gov/pubmed/25605240

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