Group I Paks as therapeutic targets in NF2-deficient meningioma

Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple tumors in the central nervous system, most notably schwannomas and meningiomas. Mutational inactivation of NF2 is found in 40–60% of sporadic meningiomas, but the molecular mechanisms underl...

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Detalles Bibliográficos
Autores principales: Chow, Hoi-Yee, Dong, Biao, Duron, Sergio G., Campbell, David A., Ong, Christy C., Hoeflich, Klaus P., Chang, Long-Sheng, Welling, D. Bradley, Yang, Zeng-jie, Chernoff, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385830/
https://www.ncbi.nlm.nih.gov/pubmed/25596744

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