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Claudin-7 promotes the epithelial – mesenchymal transition in human colorectal cancer

In colorectal cancer (CoCa) EpCAM is frequently associated with claudin-7. There is evidence that tumor-promoting EpCAM activities are modulated by the association with claudin-7. To support this hypothesis, claudin-7 was knocked-down (kd) in HT29 and SW948 cells. HT29-cld7(kd) and SW948-cld7(kd) ce...

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Detalles Bibliográficos
Autores principales: Philip, Rahel, Heiler, Sarah, Mu, Wei, Büchler, Markus W., Zöller, Margot, Thuma, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385835/
https://www.ncbi.nlm.nih.gov/pubmed/25514462