Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Hypoxia-inducible genes may contribute to therapy resistance in glioblastoma (GBM), the most aggressive and hypoxic brain tumours. It has been recently reported that erythropoietin (EPO) and its receptor (EPOR) are involved in glioma growth. We now investigated whether EPOR signalling may modulate t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérès, Elodie A., Gérault, Aurélie N., Valable, Samuel, Roussel, Simon, Toutain, Jérôme, Divoux, Didier, Guillamo, Jean-Sébastien, Sanson, Marc, Bernaudin, Myriam, Petit, Edwige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385839/
https://www.ncbi.nlm.nih.gov/pubmed/25544764

Ejemplares similares

Ejemplares similares