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RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer
Androgen receptor (AR) signaling is essential for the development of prostate cancer. Here, we report that runt-related transcription factor (RUNX1) could be a key molecule for the androgen-dependence of prostate cancer. We found RUNX1 is a target of AR and regulated positively by androgen. Our RUNX...
Autores principales: | Takayama, Ken-ichi, Suzuki, Takashi, Tsutsumi, Shuichi, Fujimura, Tetsuya, Urano, Tomohiko, Takahashi, Satoru, Homma, Yukio, Aburatani, Hiroyuki, Inoue, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385850/ https://www.ncbi.nlm.nih.gov/pubmed/25537508 |
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