By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy

Basal-like breast cancer is an aggressive tumor subtype with a poor response to conventional therapies. Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs). Here we show that miR-100 inhibits maintenance and expansion of BrCSCs in basal-like cancer through...

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Detalles Bibliográficos
Autores principales: Petrelli, Annalisa, Carollo, Rosachiara, Cargnelutti, Marilisa, Iovino, Flora, Callari, Maurizio, Cimino, Daniela, Todaro, Matilde, Mangiapane, Laura Rosa, Giammona, Alessandro, Cordova, Adriana, Montemurro, Filippo, Taverna, Daniela, Daidone, Maria Grazia, Stassi, Giorgio, Giordano, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385854/
https://www.ncbi.nlm.nih.gov/pubmed/25537513

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