Cargando…
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways
Recently, we reported that induction of the co-chaperone Bcl-2-associated athanogene 3 (BAG3) is critical for recovery of rhabdomyosarcoma (RMS) cells after proteotoxic stress upon inhibition of the two constitutive protein degradation pathways, that is, the ubiquitin-proteasome system by Bortezomib...
Autores principales: | Rapino, F, Abhari, B A, Jung, M, Fulda, S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385908/ https://www.ncbi.nlm.nih.gov/pubmed/25766331 http://dx.doi.org/10.1038/cddis.2014.584 |
Ejemplares similares
-
Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression
por: Shinzawa, Miho, et al.
Publicado: (2015) -
NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway
por: Xiang, Jianyang, et al.
Publicado: (2022) -
APPL1 regulates basal NF-κB activity by stabilizing NIK
por: Hupalowska, Anna, et al.
Publicado: (2012) -
Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer
por: Pflug, Kathryn M., et al.
Publicado: (2020) -
THE RET/PTC-3 ONCOGENE ACTIVATES CLASSICAL NF-κB BY STABILIZING NIK
por: Neely, Robert J., et al.
Publicado: (2010)