RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction

Molecular pathways underlying the neurotoxicity and production of amyloid β protein (Aβ) represent potentially promising therapeutic targets for Alzheimer's disease (AD). We recently found that overexpression of the scaffolding protein RanBP9 increases Aβ production in cell lines and in transge...

Descripción completa

Detalles Bibliográficos
Autores principales: Woo, J A, Boggess, T, Uhlar, C, Wang, X, Khan, H, Cappos, G, Joly-Amado, A, De Narvaez, E, Majid, S, Minamide, L S, Bamburg, J R, Morgan, D, Weeber, E, Kang, D E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385917/
https://www.ncbi.nlm.nih.gov/pubmed/25741591
http://dx.doi.org/10.1038/cddis.2015.37

Ejemplares similares

Ejemplares similares