Cargando…

Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction

Neuropeptides induce signal transduction across the plasma membrane by acting through cell-surface receptors. The dynorphins, endogenous ligands for opioid receptors, are an exception; they also produce non-receptor-mediated effects causing pain and neurodegeneration. To understand non-receptor mech...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maximyuk, O, Khmyz, V, Lindskog, C-J, Vukojević, V, Ivanova, T, Bazov, I, Hauser, K F, Bakalkin, G, Krishtal, O
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385918/ https://www.ncbi.nlm.nih.gov/pubmed/25766322 http://dx.doi.org/10.1038/cddis.2015.39

Ejemplares similares

Temperature increase significantly enhances nociceptive responses of C-fibers to ATP, high K(+), and acidic pH in mice
por: Tkachenko, Yurii, et al.
Publicado: (2023)

Acid-sensing ion channel blocker diminazene facilitates proton-induced excitation of afferent nerves in a similar manner that Na(+)/H(+) exchanger blockers do
por: Tkachenko, Yurii, et al.
Publicado: (2023)

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
por: Sarkisyan, Daniil, et al.
Publicado: (2015)

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment
por: Kuzmin, A, et al.
Publicado: (2013)

Acid-Sensing Ion Channels: Focus on Physiological and Some Pathological Roles in the Brain
por: Storozhuk, Maksim, et al.
Publicado: (2021)

Epigenetic and Transcriptional Control of the Opioid Prodynorphine Gene: In-Depth Analysis in the Human Brain
por: Nosova, Olga, et al.
Publicado: (2021)

Engineering monolayer poration for rapid exfoliation of microbial membranes
por: Pyne, Alice, et al.
Publicado: (2017)

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics
por: Bazov, Igor, et al.
Publicado: (2018)

Polymersome Poration and Rupture Mediated by Plasmonic Nanoparticles in Response to Single-Pulse Irradiation
por: DiSalvo, Gina M., et al.
Publicado: (2020)

Left-Right Side-Specific Neuropeptide Mechanism Mediates Contralateral Responses to a Unilateral Brain Injury
por: Watanabe, Hiroyuki, et al.
Publicado: (2021)

Triggering of Major Brain Disorders by Protons and ATP: The Role of ASICs and P2X Receptors
por: Cherninskyi, Andrii, et al.
Publicado: (2022)

Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms
por: Pfeil, Marc-Philipp, et al.
Publicado: (2018)

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics
por: Bazov, Igor, et al.
Publicado: (2018)

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation
por: Vanstone, Simon, et al.
Publicado: (2019)

Live Cell Poration by Au Nanostars to Probe Intracellular Molecular Composition with SERS
por: Nikelshparg, Evelina I., et al.
Publicado: (2021)

Highly Efficient Macromolecule-Sized Poration of Lipid Bilayers by a Synthetically Evolved Peptide
por: Wiedman, Gregory, et al.
Publicado: (2014)

PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties
por: Leite, Natália Bueno, et al.
Publicado: (2015)

Author Correction: Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms
por: Pfeil, Marc-Philipp, et al.
Publicado: (2018)

Flowering Poration—A Synergistic Multi-Mode Antibacterial Mechanism by a Bacteriocin Fold
por: Hammond, Katharine, et al.
Publicado: (2020)

Sequential Water and Headgroup Merger: Membrane Poration Paths and Energetics from MD Simulations
por: Bubnis, Greg, et al.
Publicado: (2020)

Effects of cholesterol on the anionic magnetite nanoparticle-induced deformation and poration of giant lipid vesicles
por: Akter, Salma, et al.
Publicado: (2022)

Influence of sugar concentration on the vesicle compactness, deformation and membrane poration induced by anionic nanoparticles
por: Hasan, Sharif, et al.
Publicado: (2022)

Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences
por: Taqi, Malik Mumtaz, et al.
Publicado: (2012)

Tumour Cell Membrane Poration and Ablation by Pulsed Low-Intensity Electric Field with Carbon Nanotubes
por: Wang, Lijun, et al.
Publicado: (2015)

Planar aggregation of the influenza viral fusion peptide alters membrane structure and hydration, promoting poration
por: Rice, Amy, et al.
Publicado: (2022)

Morphine Exacerbates HIV-1 Tat-Induced Cytokine Production in Astrocytes through Convergent Effects on [Ca(2+)](i), NF-κB Trafficking and Transcription
por: El-Hage, Nazira, et al.
Publicado: (2008)

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics
por: Jin, Zhe, et al.
Publicado: (2012)

Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors
por: Zapukhliak, Olha, et al.
Publicado: (2021)

Effects of polyethylene glycol-grafted phospholipid on the anionic magnetite nanoparticles-induced deformation and poration in giant lipid vesicles
por: Karal, Mohammad Abu Sayem, et al.
Publicado: (2023)

The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia
por: Lubejko, Susan T., et al.
Publicado: (2022)

Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis
por: Xu, Xiaofang, et al.
Publicado: (2021)

Functional modulation of human delta opioid receptor by neuropeptide FF
por: Änkö, Minna-Liisa, et al.
Publicado: (2005)

Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system
por: Sirohi, Sunil, et al.
Publicado: (2012)

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics
por: Jin, Zhe, et al.
Publicado: (2014)

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics
por: Jin, Zhe, et al.
Publicado: (2014)

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics
por: Bhandage, Amol K., et al.
Publicado: (2014)

PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models*
por: Anapindi, Krishna D.B., et al.
Publicado: (2019)

Vaspin (but not neuropeptide B or neuropeptide W) as a possible predictor of body weight normalization in anorexia nervosa
por: Grzelak, Teresa, et al.
Publicado: (2018)

Molecular dynamics exploration of poration and leaking caused by Kalata B1 in HIV-infected cell membrane compared to host and HIV membranes
por: Nawae, Wanapinun, et al.
Publicado: (2017)

Neuropeptides at the crossroad of fear and hunger: a special focus on neuropeptide Y
por: Comeras, Lucas B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nj8ara3a0uoeb26lqbiiimat6g