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T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance

Hepatitis B virus (HBV) infection is the major cause of inflammatory liver disease, of which the clinical recovery and effective anti-viral therapy is associated with the sustained viral control of effector T cells. In humans, chronic HBV infection often shows weak or absent virus-specific T-cell re...

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Detalles Bibliográficos
Autores principales: Ye, B, Liu, X, Li, X, Kong, H, Tian, L, Chen, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385920/
https://www.ncbi.nlm.nih.gov/pubmed/25789969
http://dx.doi.org/10.1038/cddis.2015.42