Reactive oxygen species and p21(Waf1/Cip1) are both essential for p53-mediated senescence of head and neck cancer cells

Treatment of head and neck squamous cell carcinoma, HNSCC, often requires multimodal therapy, including radiation therapy. The efficacy of radiotherapy in controlling locoregional recurrence, the most frequent cause of death from HNSCC, is critically important for patient survival. One potential bio...

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Detalles Bibliográficos
Autores principales: Fitzgerald, A L, Osman, A A, Xie, T-X, Patel, A, Skinner, H, Sandulache, V, Myers, J N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385922/
https://www.ncbi.nlm.nih.gov/pubmed/25766317
http://dx.doi.org/10.1038/cddis.2015.44

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