KLF17 empowers TGF-β/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression

Inhibition of tumor suppressive signaling is linked to cancer progression, metastasis and epithelial–mesenchymal transition (EMT). Transforming growth factor-β1 (TGF-β)/Smad signaling plays an important role in tumor suppression. Kruppel-like-factor 17 (KLF17) is a negative regulator of metastasis a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, A, Zhang, P, Liangfang, Y, Wenshe, S, Wang, H, Lin, X, Dai, Y, Feng, X-h, Moses, R, Wang, D, Li, X, Xiao, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385926/
https://www.ncbi.nlm.nih.gov/pubmed/25766320
http://dx.doi.org/10.1038/cddis.2015.48

Ejemplares similares

Ejemplares similares