Muscle-building supplement use and increased risk of testicular germ cell cancer in men from Connecticut and Massachusetts

BACKGROUND: No analytic epidemiological study has examined the relationship between use of muscle-building supplements (MBSs) and testicular germ cell cancer (TGCC) risk. METHODS: We conducted a population-based case–control study including 356 TGCC cases and 513 controls from Connecticut and Massac...

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Detalles Bibliográficos
Autores principales: Li, N, Hauser, R, Holford, T, Zhu, Y, Zhang, Y, Bassig, B A, Honig, S, Chen, C, Boyle, P, Dai, M, Schwartz, S M, Morey, P, Sayward, H, Hu, Z, Shen, H, Gomery, P, Zheng, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385953/
https://www.ncbi.nlm.nih.gov/pubmed/25826226
http://dx.doi.org/10.1038/bjc.2015.26
Descripción
Sumario:BACKGROUND: No analytic epidemiological study has examined the relationship between use of muscle-building supplements (MBSs) and testicular germ cell cancer (TGCC) risk. METHODS: We conducted a population-based case–control study including 356 TGCC cases and 513 controls from Connecticut and Massachusetts. RESULTS: The odds ratio (OR) for ever use of MBSs in relation to risk of TGCC was significantly elevated (OR=1.65, 95% confidence interval (CI): 1.11–2.46). The associations were significantly stronger among early users, men with more types of MBSs used, and longer periods of use. CONCLUSIONS: MBS use is a potentially modifiable risk factor that may be associated with TGCC.

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