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IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma
BACKGROUND: We evaluated germline single nucleotide polymorphisms (SNPs) for association with overall survival (OS) in pazopanib- or sunitinib-treated patients with advanced renal cell carcinoma (aRCC). METHODS: The discovery analysis tested 27 SNPs within 13 genes from a phase III pazopanib trial (...
Autores principales: | Xu, C-F, Johnson, T, Garcia-Donas, J, Choueiri, T K, Sternberg, C N, Davis, I D, Bing, N, Deen, K C, Xue, Z, McCann, L, Esteban, E, Whittaker, J C, Spraggs, C F, Rodríguez-Antona, C, Pandite, L N, Motzer, R J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385958/ https://www.ncbi.nlm.nih.gov/pubmed/25695485 http://dx.doi.org/10.1038/bjc.2015.64 |
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