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TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells

BACKGROUND: The Par complex – comprising partition-defective 6 (Par6), Par3, and atypical protein kinase C (aPKC) – is crucial for cell polarisation, the loss of which contributes to cancer progression. Transforming growth factor β (TGFβ)-induced phosphorylation of Par6 on the conserved serine 345 i...

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Detalles Bibliográficos
Autores principales:	Mu, Y, Zang, G, Engström, U, Busch, C, Landström, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385960/ https://www.ncbi.nlm.nih.gov/pubmed/25756394 http://dx.doi.org/10.1038/bjc.2015.71

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