A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine

Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of...

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Autores principales: Belhekar, Mahesh N., Pai, Sarayu, Tayade, Parimal, Dalwadi, Pradip, Munshi, Renuka, Varthakavi, Prema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386139/
https://www.ncbi.nlm.nih.gov/pubmed/25878390
http://dx.doi.org/10.4103/0253-7613.153438
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author Belhekar, Mahesh N.
Pai, Sarayu
Tayade, Parimal
Dalwadi, Pradip
Munshi, Renuka
Varthakavi, Prema
author_facet Belhekar, Mahesh N.
Pai, Sarayu
Tayade, Parimal
Dalwadi, Pradip
Munshi, Renuka
Varthakavi, Prema
author_sort Belhekar, Mahesh N.
collection PubMed
description Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of human insulin produced by recombinant deoxyribonucleic acid technology. Here, we present a case of Type 2 DM who demonstrated immediate (Type 1) hypersensitivity reaction on the sites of subcutaneous injection of soluble and isophane insulin but insulin glargine was tolerated well and provided good glycemic control.
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spelling pubmed-43861392015-04-15 A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine Belhekar, Mahesh N. Pai, Sarayu Tayade, Parimal Dalwadi, Pradip Munshi, Renuka Varthakavi, Prema Indian J Pharmacol Drug Watch Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of human insulin produced by recombinant deoxyribonucleic acid technology. Here, we present a case of Type 2 DM who demonstrated immediate (Type 1) hypersensitivity reaction on the sites of subcutaneous injection of soluble and isophane insulin but insulin glargine was tolerated well and provided good glycemic control. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4386139/ /pubmed/25878390 http://dx.doi.org/10.4103/0253-7613.153438 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Belhekar, Mahesh N.
Pai, Sarayu
Tayade, Parimal
Dalwadi, Pradip
Munshi, Renuka
Varthakavi, Prema
A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title_full A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title_fullStr A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title_full_unstemmed A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title_short A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
title_sort case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386139/
https://www.ncbi.nlm.nih.gov/pubmed/25878390
http://dx.doi.org/10.4103/0253-7613.153438
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