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Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia

OBJECTIVES: To determine the body mass, cardiovascular and metabolic characteristics of young people presenting for mental healthcare. DESIGN: Cross-sectional assessments of body mass, cardiovascular and metabolic risk factors. SETTING: Two primary-care based sites in Sydney, Australia for young peo...

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Autores principales: Scott, Elizabeth M, Hermens, Daniel F, White, Django, Naismith, Sharon L, GeHue, Jeanne, Whitwell, Bradley G, Glozier, Nick, Hickie, Ian B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386215/
https://www.ncbi.nlm.nih.gov/pubmed/25818274
http://dx.doi.org/10.1136/bmjopen-2014-007066
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author Scott, Elizabeth M
Hermens, Daniel F
White, Django
Naismith, Sharon L
GeHue, Jeanne
Whitwell, Bradley G
Glozier, Nick
Hickie, Ian B
author_facet Scott, Elizabeth M
Hermens, Daniel F
White, Django
Naismith, Sharon L
GeHue, Jeanne
Whitwell, Bradley G
Glozier, Nick
Hickie, Ian B
author_sort Scott, Elizabeth M
collection PubMed
description OBJECTIVES: To determine the body mass, cardiovascular and metabolic characteristics of young people presenting for mental healthcare. DESIGN: Cross-sectional assessments of body mass, cardiovascular and metabolic risk factors. SETTING: Two primary-care based sites in Sydney, Australia for young people in the early stages of mental disorders. PARTICIPANTS: A clinical sample of young people (12–30 years) with mental health problems. OUTCOME MEASURES: Daily smoking rates, body mass index (BMI), blood glucose and lipids, blood pressure (BP) and pulse rate. RESULTS: Of 1005 young people who had their BMI determined (62% female; 19.0±3.5 years), three quarters (739/1005) also had BP recordings and one-third (298/1005) had blood sampling. Clinically, 775 were assigned to one of three diagnostic categories (anxious-depression: n=541; mania-fatigue, n=104; developmental-psychotic n=130). The profile of BMI categories approximated that of the comparable segments of the Australian population. Older age, lower levels of social functioning and higher systolic BP were all associated with high BMI. In a subset (n=129), current use of any psychotropic medication was associated (p<0.05) with increased BMI. Almost one-third of cases were current daily smokers (compared to population rate of 11%). Males had a higher proportion of raised glucose and high-density lipoprotein (HDL) compared to females (9.3% and 34.1% vs 2.1% and 5.9%, respectively). Overall, there was no relationship between BMI and fasting glucose but significant relationships with triglycerides and HDL were noted. Furthermore, there were no significant relationships between diagnostic subgroup and metabolic profiles. CONCLUSIONS: Daily smoking rates are increased among young people presenting for mental healthcare. However, these young people do not demonstrate adverse cardiometabolic profiles. The high levels of smoking, and association of BMI with adverse social circumstances, suggest that risk factors for chronic disease are already present and likely to be compounded by medication and social disadvantage.
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spelling pubmed-43862152015-04-10 Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia Scott, Elizabeth M Hermens, Daniel F White, Django Naismith, Sharon L GeHue, Jeanne Whitwell, Bradley G Glozier, Nick Hickie, Ian B BMJ Open Mental Health OBJECTIVES: To determine the body mass, cardiovascular and metabolic characteristics of young people presenting for mental healthcare. DESIGN: Cross-sectional assessments of body mass, cardiovascular and metabolic risk factors. SETTING: Two primary-care based sites in Sydney, Australia for young people in the early stages of mental disorders. PARTICIPANTS: A clinical sample of young people (12–30 years) with mental health problems. OUTCOME MEASURES: Daily smoking rates, body mass index (BMI), blood glucose and lipids, blood pressure (BP) and pulse rate. RESULTS: Of 1005 young people who had their BMI determined (62% female; 19.0±3.5 years), three quarters (739/1005) also had BP recordings and one-third (298/1005) had blood sampling. Clinically, 775 were assigned to one of three diagnostic categories (anxious-depression: n=541; mania-fatigue, n=104; developmental-psychotic n=130). The profile of BMI categories approximated that of the comparable segments of the Australian population. Older age, lower levels of social functioning and higher systolic BP were all associated with high BMI. In a subset (n=129), current use of any psychotropic medication was associated (p<0.05) with increased BMI. Almost one-third of cases were current daily smokers (compared to population rate of 11%). Males had a higher proportion of raised glucose and high-density lipoprotein (HDL) compared to females (9.3% and 34.1% vs 2.1% and 5.9%, respectively). Overall, there was no relationship between BMI and fasting glucose but significant relationships with triglycerides and HDL were noted. Furthermore, there were no significant relationships between diagnostic subgroup and metabolic profiles. CONCLUSIONS: Daily smoking rates are increased among young people presenting for mental healthcare. However, these young people do not demonstrate adverse cardiometabolic profiles. The high levels of smoking, and association of BMI with adverse social circumstances, suggest that risk factors for chronic disease are already present and likely to be compounded by medication and social disadvantage. BMJ Publishing Group 2015-03-27 /pmc/articles/PMC4386215/ /pubmed/25818274 http://dx.doi.org/10.1136/bmjopen-2014-007066 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Mental Health
Scott, Elizabeth M
Hermens, Daniel F
White, Django
Naismith, Sharon L
GeHue, Jeanne
Whitwell, Bradley G
Glozier, Nick
Hickie, Ian B
Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title_full Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title_fullStr Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title_full_unstemmed Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title_short Body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in Sydney, Australia
title_sort body mass, cardiovascular risk and metabolic characteristics of young persons presenting for mental healthcare in sydney, australia
topic Mental Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386215/
https://www.ncbi.nlm.nih.gov/pubmed/25818274
http://dx.doi.org/10.1136/bmjopen-2014-007066
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