Cargando…
Developmental Regulation and Induction of Cytochrome P450 2W1, an Enzyme Expressed in Colon Tumors
Cytochrome P450 2W1 (CYP2W1) is expressed predominantly in colorectal and also in hepatic tumors, whereas the levels are insignificant in the corresponding normal human adult tissues. CYP2W1 has been proposed as an attractive target for colorectal cancer (CRC) therapy by exploiting its ability to ac...
Autores principales: | Choong, Eva, Guo, Jia, Persson, Anna, Virding, Susanne, Johansson, Inger, Mkrtchian, Souren, Ingelman-Sundberg, Magnus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386763/ https://www.ncbi.nlm.nih.gov/pubmed/25844926 http://dx.doi.org/10.1371/journal.pone.0122820 |
Ejemplares similares
-
Intronic polymorphisms of cytochromes P450
por: Ingelman-Sundberg, Magnus, et al.
Publicado: (2010) -
Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas
por: Nolé, Paola, et al.
Publicado: (2016) -
Integrating rare genetic variants into pharmacogenetic drug response predictions
por: Ingelman-Sundberg, Magnus, et al.
Publicado: (2018) -
The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects
por: Sim, Sarah C, et al.
Publicado: (2010) -
Worldwide Distribution of Cytochrome P450 Alleles: A Meta‐analysis of Population‐scale Sequencing Projects
por: Zhou, Y, et al.
Publicado: (2017)