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Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4

Correct localization of membrane proteins is essential to all cells. Chaperone cascades coordinate the capture and handover of substrate proteins from the ribosome to their target membrane; yet the mechanistic and structural details of these processes remain unclear. Here we investigate the conserve...

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Detalles Bibliográficos
Autores principales: Gristick, Harry B., Rao, Meera, Chartron, Justin W., Rome, Michael E., Shan, Shu-ou, Clemons, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386898/
https://www.ncbi.nlm.nih.gov/pubmed/24727835
http://dx.doi.org/10.1038/nsmb.2813