The role of TLR8 signaling in Acute Myeloid Leukemia Differentiation

Acute myeloid leukemia (AML) is an aggressive disease with a poor 5-year survival of 21% that is characterized by a differentiation arrest of immature myeloid cells. For a rare subtype of AML (acute promyeloctyic leukemia, 5-10% of cases) all-trans retinoic acid therapy removes the differentiation b...

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Detalles Bibliográficos
Autores principales: Ignatz-Hoover, James J, Wang, Huaiyu, Moreton, Stephen A, Chakrabarti, Amit, Agarwal, Mukesh K, Sun, Kevin, Gupta, Kalpana, Wald, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387126/
https://www.ncbi.nlm.nih.gov/pubmed/25283842
http://dx.doi.org/10.1038/leu.2014.293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387126/
https://www.ncbi.nlm.nih.gov/pubmed/25283842
http://dx.doi.org/10.1038/leu.2014.293

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