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The role of TLR8 signaling in Acute Myeloid Leukemia Differentiation

Acute myeloid leukemia (AML) is an aggressive disease with a poor 5-year survival of 21% that is characterized by a differentiation arrest of immature myeloid cells. For a rare subtype of AML (acute promyeloctyic leukemia, 5-10% of cases) all-trans retinoic acid therapy removes the differentiation b...

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Detalles Bibliográficos
Autores principales:	Ignatz-Hoover, James J, Wang, Huaiyu, Moreton, Stephen A, Chakrabarti, Amit, Agarwal, Mukesh K, Sun, Kevin, Gupta, Kalpana, Wald, David N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387126/ https://www.ncbi.nlm.nih.gov/pubmed/25283842 http://dx.doi.org/10.1038/leu.2014.293

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