The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications

Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evid...

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Autores principales: Keyhanmanesh, Rana, Gholamnezhad, Zahra, Boskabady, Mohammad Hossien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387229/
https://www.ncbi.nlm.nih.gov/pubmed/25859297
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author Keyhanmanesh, Rana
Gholamnezhad, Zahra
Boskabady, Mohammad Hossien
author_facet Keyhanmanesh, Rana
Gholamnezhad, Zahra
Boskabady, Mohammad Hossien
author_sort Keyhanmanesh, Rana
collection PubMed
description Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evidence of the relaxant effects of this plant and some of its constituents on different types of smooth muscle including rabbit aorta, rabbit jejunum and trachea. The relaxant effect of N. sativa could be of therapeutic importance such as bronchodilation in asthma, vasodilation in hypertension and therapeutic effect on digestive or urogenital disorders. Therefore in the present article, the relaxant effects of N. sativa and its constituents on smooth muscles and its possible mechanisms as well as clinical application of this effect were reviewed.
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spelling pubmed-43872292015-04-09 The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications Keyhanmanesh, Rana Gholamnezhad, Zahra Boskabady, Mohammad Hossien Iran J Basic Med Sci Review Article Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evidence of the relaxant effects of this plant and some of its constituents on different types of smooth muscle including rabbit aorta, rabbit jejunum and trachea. The relaxant effect of N. sativa could be of therapeutic importance such as bronchodilation in asthma, vasodilation in hypertension and therapeutic effect on digestive or urogenital disorders. Therefore in the present article, the relaxant effects of N. sativa and its constituents on smooth muscles and its possible mechanisms as well as clinical application of this effect were reviewed. Mashhad University of Medical Sciences 2014-12 /pmc/articles/PMC4387229/ /pubmed/25859297 Text en Copyright: © Iranian Journal of Basic Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Keyhanmanesh, Rana
Gholamnezhad, Zahra
Boskabady, Mohammad Hossien
The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title_full The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title_fullStr The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title_full_unstemmed The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title_short The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications
title_sort relaxant effect of nigella sativa on smooth muscles, its possible mechanisms and clinical applications
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387229/
https://www.ncbi.nlm.nih.gov/pubmed/25859297
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