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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1
Splenic myelopoiesis provides a steady flow of leukocytes to inflamed tissues, and leukocytosis correlates with cardiovascular mortality. Yet regulation of hematopoietic stem cell (HSC) activity in the spleen is incompletely understood. Here, we show that red pulp vascular cell adhesion molecule 1 (...
Autores principales: | Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S., Sager, Hendrik B., Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana, Ruda, Vera M., Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387283/ https://www.ncbi.nlm.nih.gov/pubmed/25800955 http://dx.doi.org/10.1084/jem.20141642 |
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