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BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
Follicular helper T cells (Tfh cells) are required for T cell help to B cells, and BCL6 is the defining transcription factor of Tfh cells. However, the functions of BCL6 in Tfh cells have largely remained unclear. Here we defined the BCL6 cistrome in primary human germinal center Tfh cells to assess...
Autores principales: | Hatzi, Katerina, Nance, J. Philip, Kroenke, Mark A., Bothwell, Marcella, Haddad, Elias K., Melnick, Ari, Crotty, Shane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387288/ https://www.ncbi.nlm.nih.gov/pubmed/25824819 http://dx.doi.org/10.1084/jem.20141380 |
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