Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays

The optimal radiation schedule for primary cutaneous anaplastic lymphoma (PCALCL) has not been investigated. We report here satisfactory outcomes of low-dose (16-20 Gy, 3-5 fractions), superficial X-ray radiation (40-50 kV) in a series of 10 patients with PCALCL. Only 1 patient developed a local rel...

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Detalles Bibliográficos
Autores principales: Jepsen, Malene E., Gniadecki, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387335/
https://www.ncbi.nlm.nih.gov/pubmed/25918620
http://dx.doi.org/10.4081/dr.2015.5888
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author Jepsen, Malene E.
Gniadecki, Robert
author_facet Jepsen, Malene E.
Gniadecki, Robert
author_sort Jepsen, Malene E.
collection PubMed
description The optimal radiation schedule for primary cutaneous anaplastic lymphoma (PCALCL) has not been investigated. We report here satisfactory outcomes of low-dose (16-20 Gy, 3-5 fractions), superficial X-ray radiation (40-50 kV) in a series of 10 patients with PCALCL. Only 1 patient developed a local relapse during the median observation time of 25 months; complete remission was recorded in the other patients. This observation indicates that superficial, low dose X-ray therapy may provide a cost-effective alternative to the traditional 35-45 Gy schedules.
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spelling pubmed-43873352015-04-27 Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays Jepsen, Malene E. Gniadecki, Robert Dermatol Reports Article The optimal radiation schedule for primary cutaneous anaplastic lymphoma (PCALCL) has not been investigated. We report here satisfactory outcomes of low-dose (16-20 Gy, 3-5 fractions), superficial X-ray radiation (40-50 kV) in a series of 10 patients with PCALCL. Only 1 patient developed a local relapse during the median observation time of 25 months; complete remission was recorded in the other patients. This observation indicates that superficial, low dose X-ray therapy may provide a cost-effective alternative to the traditional 35-45 Gy schedules. PAGEPress Publications, Pavia, Italy 2015-03-16 /pmc/articles/PMC4387335/ /pubmed/25918620 http://dx.doi.org/10.4081/dr.2015.5888 Text en ©Copyright M.E. Jepsen and R. Gniadecki http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Jepsen, Malene E.
Gniadecki, Robert
Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title_full Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title_fullStr Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title_full_unstemmed Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title_short Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
title_sort treatment of primary cutaneous anaplastic large cell lymphoma with superficial x-rays
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387335/
https://www.ncbi.nlm.nih.gov/pubmed/25918620
http://dx.doi.org/10.4081/dr.2015.5888
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