A Recurrent Giant Cell Tumor of Bone Treated with Denosumab

Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthes...

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Detalles Bibliográficos
Autores principales: Stadler, Nicola, Fingernagel, Thomas, Hofstaetter, Stefan G., Trieb, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387340/
https://www.ncbi.nlm.nih.gov/pubmed/25918628
http://dx.doi.org/10.4081/cp.2015.697
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author Stadler, Nicola
Fingernagel, Thomas
Hofstaetter, Stefan G.
Trieb, Klemens
author_facet Stadler, Nicola
Fingernagel, Thomas
Hofstaetter, Stefan G.
Trieb, Klemens
author_sort Stadler, Nicola
collection PubMed
description Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclear factor kappa-B ligand inhibitor. In this case report we want to present a new option to treat this kind of neoplasm.
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spelling pubmed-43873402015-04-27 A Recurrent Giant Cell Tumor of Bone Treated with Denosumab Stadler, Nicola Fingernagel, Thomas Hofstaetter, Stefan G. Trieb, Klemens Clin Pract Case Report Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclear factor kappa-B ligand inhibitor. In this case report we want to present a new option to treat this kind of neoplasm. PAGEPress Publications, Pavia, Italy 2015-02-10 /pmc/articles/PMC4387340/ /pubmed/25918628 http://dx.doi.org/10.4081/cp.2015.697 Text en ©Copyright N. Stadler et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Stadler, Nicola
Fingernagel, Thomas
Hofstaetter, Stefan G.
Trieb, Klemens
A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title_full A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title_fullStr A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title_full_unstemmed A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title_short A Recurrent Giant Cell Tumor of Bone Treated with Denosumab
title_sort recurrent giant cell tumor of bone treated with denosumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387340/
https://www.ncbi.nlm.nih.gov/pubmed/25918628
http://dx.doi.org/10.4081/cp.2015.697
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