Paraneoplastic Autoimmune Hemolytic Anemia in Ovarian Cancer: A Marker of Disease Activity

Autoimmune hemolytic anemia (AIHA) is a rare paraneoplastic syndrome associated with ovarian malignancies. We report a case of a 77 year-old female with metastatic ovarian carcinoma who presented with worsening anemia from her baseline, and was found to have a warm autoimmune hemolytic anemia. We pe...

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Detalles Bibliográficos
Autores principales: Loh, Kah Poh, Kansagra, Ankit, Asik, Armen, Ali, Syed, Dahiya, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387350/
https://www.ncbi.nlm.nih.gov/pubmed/25918604
http://dx.doi.org/10.4081/rt.2015.5598
Descripción
Sumario:Autoimmune hemolytic anemia (AIHA) is a rare paraneoplastic syndrome associated with ovarian malignancies. We report a case of a 77 year-old female with metastatic ovarian carcinoma who presented with worsening anemia from her baseline, and was found to have a warm autoimmune hemolytic anemia. We performed a literature review and analyzed all 10 cases (including our patient) that have been reported to date, and incorporated the clinical presentation, histology and stage of underlying malignancies, types, treatment, prognosis and mechanisms of AIHA in ovarian carcinoma.

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