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CARMing down the SINEs of anarchy: two paths to freedom from paraspeckle detention

A subset of messenger RNAs (mRNAs) that contain inverted Alu elements in their 3′ untranslated region are inefficiently exported to the cytoplasm and retained in subnuclear bodies called paraspeckles. The arginine methyltransferase CARM1 (coactivator-associated arginine methyltransferase 1) promotes...

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Detalles Bibliográficos
Autores principales: Elbarbary, Reyad A., Maquat, Lynne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387710/
https://www.ncbi.nlm.nih.gov/pubmed/25838539
http://dx.doi.org/10.1101/gad.261438.115