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Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells

Cystic fibrosis (CF) is a lethal disease caused by mutations in the chloride channel CFTR gene. The disease is characterized by decreased chloride secretion and unregulated sodium absorption through the epithelial sodium channel (ENaC) in the airway epithelium and other affected organs. We hypothesi...

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Detalles Bibliográficos
Autores principales: Henry, Katherine R., Lee, Seakwoo, Walker, Douglas, Zeitlin, Pamela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387756/
https://www.ncbi.nlm.nih.gov/pubmed/25626868
http://dx.doi.org/10.14814/phy2.12264

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