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Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns
Hemolytic uremic syndrome (HUS) from enterohemorrhagic Escherichia coli infection is a leading cause of kidney failure in otherwise healthy U.S. children. The bacterial Shiga toxins (Stx) induce the characteristic coagulopathy of HUS, but the damage to toxin-receptor expressing cells and organ injur...
Autores principales: | Mayer, Chad L., Parello, Caitlin S. L., Lee, Benjamin C., Itagaki, Kiyoshi, Kurosawa, Shinichiro, Stearns-Kurosawa, Deborah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387861/ https://www.ncbi.nlm.nih.gov/pubmed/25904918 http://dx.doi.org/10.3389/fimmu.2015.00155 |
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