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Potassium Channel Activator Attenuates Salicylate-Induced Cochlear Hearing Loss Potentially Ameliorating Tinnitus
High dose sodium salicylate causes moderate, reversible hearing loss and tinnitus. Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) and/or reduction of KCNQ4 potassium currents in OHCs, which decreases the driving force fo...
Autores principales: | Sun, Wei, Liu, Jun, Zhang, Chao, Zhou, Na, Manohar, Senthilvelan, Winchester, Wendy, Miranda, Jason A., Salvi, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387930/ https://www.ncbi.nlm.nih.gov/pubmed/25904892 http://dx.doi.org/10.3389/fneur.2015.00077 |
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