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Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod–Zwilch–ZW10 (RZZ) complex
The spindle-assembly checkpoint (SAC) monitors kinetochore–microtubule attachment during mitosis. In metazoans, the three-subunit Rod–Zwilch–ZW10 (RZZ) complex is a crucial SAC component that interacts with additional SAC-activating and SAC-silencing components, including the Mad1–Mad2 complex and c...
Autores principales: | Altenfeld, Anika, Wohlgemuth, Sabine, Wehenkel, Annemarie, Vetter, Ingrid R., Musacchio, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388180/ https://www.ncbi.nlm.nih.gov/pubmed/25849506 http://dx.doi.org/10.1107/S2053230X15004343 |
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