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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Structural analysis of protein fibrillation is inherently challenging. Given the crucial role of fibrils in amyloid diseases, method advancement is urgently needed. A hybrid modelling approach is presented enabling detailed analysis of a highly ordered and hierarchically organized fibril of the GNNQ...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388266/ https://www.ncbi.nlm.nih.gov/pubmed/25849399 http://dx.doi.org/10.1107/S1399004715001674 |