Probing ADAMTS13 Substrate Specificity using Phage Display

Von Willebrand factor (VWF) is a large, multimeric protein that regulates hemostasis by tethering platelets to the subendothelial matrix at sites of vascular damage. The procoagulant activity of plasma VWF correlates with the length of VWF multimers, which is proteolytically controlled by the metall...

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Detalles Bibliográficos
Autores principales: Desch, Karl C., Kretz, Colin, Yee, Andrew, Gildersleeve, Robert, Metzger, Kristin, Agrawal, Nidhi, Cheng, Jane, Ginsburg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388381/
https://www.ncbi.nlm.nih.gov/pubmed/25849793
http://dx.doi.org/10.1371/journal.pone.0122931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388381/
https://www.ncbi.nlm.nih.gov/pubmed/25849793
http://dx.doi.org/10.1371/journal.pone.0122931

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