Cargando…
Probing ADAMTS13 Substrate Specificity using Phage Display
Von Willebrand factor (VWF) is a large, multimeric protein that regulates hemostasis by tethering platelets to the subendothelial matrix at sites of vascular damage. The procoagulant activity of plasma VWF correlates with the length of VWF multimers, which is proteolytically controlled by the metall...
Autores principales: | Desch, Karl C., Kretz, Colin, Yee, Andrew, Gildersleeve, Robert, Metzger, Kristin, Agrawal, Nidhi, Cheng, Jane, Ginsburg, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388381/ https://www.ncbi.nlm.nih.gov/pubmed/25849793 http://dx.doi.org/10.1371/journal.pone.0122931 |
Ejemplares similares
-
High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13
por: Kretz, Colin A., et al.
Publicado: (2018) -
Mechanisms of ADAMTS13 regulation
por: DeYoung, Veronica, et al.
Publicado: (2022) -
Systemic antithrombotic effects of ADAMTS13
por: Chauhan, Anil K., et al.
Publicado: (2006) -
Crystal structure and substrate-induced activation of ADAMTS13
por: Petri, Anastasis, et al.
Publicado: (2019) -
Identification of Calpain Substrates by ORF Phage Display
por: Caberoy, Nora B., et al.
Publicado: (2011)