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Potential Role of Notch Signalling in CD34(+) Chronic Myeloid Leukaemia Cells: Cross-Talk between Notch and BCR-ABL

Notch signalling is critical for haemopoietic stem cell (HSC) self-renewal and survival. The role of Notch signalling has been reported recently in chronic myeloid leukaemia (CML) – a stem cell disease characterized by BCR-ABL tyrosine kinase activation. Therefore, we studied the relationship betwee...

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Detalles Bibliográficos
Autores principales:	Aljedai, Abdullah, Buckle, Anne-Marie, Hiwarkar, Prashant, Syed, Farhatullah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388554/ https://www.ncbi.nlm.nih.gov/pubmed/25849484 http://dx.doi.org/10.1371/journal.pone.0123016

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