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TAp63γ and ΔNp63β Promote Osteoblastic Differentiation of Human Mesenchymal Stem Cells: Regulation by Vitamin D3 Metabolites

The transcription factor p63 is required for skeletal formation, and is important for the regulation of 1α,25(OH)(2)D(3) receptor (VDR) in human mesenchymal stem cells (hMSC). Herein we report that TAp63γ and ΔNp63β appear to be an integral part of the osteoblastic differentiation of hMSC and are di...

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Detalles Bibliográficos
Autores principales: Curtis, Kevin M., Aenlle, Kristina K., Frisch, Rachel N., Howard, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388628/
https://www.ncbi.nlm.nih.gov/pubmed/25849854
http://dx.doi.org/10.1371/journal.pone.0123642