TGF-β1-Mediated Differentiation of Fibroblasts Is Associated with Increased Mitochondrial Content and Cellular Respiration

OBJECTIVS: Cytokine-dependent activation of fibroblasts to myofibroblasts, a key event in fibrosis, is accompanied by phenotypic changes with increased secretory and contractile properties dependent on increased energy utilization, yet changes in the energetic profile of these cells are not fully de...

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Detalles Bibliográficos
Autores principales: Negmadjanov, Ulugbek, Godic, Zarko, Rizvi, Farhan, Emelyanova, Larisa, Ross, Gracious, Richards, John, Holmuhamedov, Ekhson L., Jahangir, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388650/
https://www.ncbi.nlm.nih.gov/pubmed/25849590
http://dx.doi.org/10.1371/journal.pone.0123046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388650/
https://www.ncbi.nlm.nih.gov/pubmed/25849590
http://dx.doi.org/10.1371/journal.pone.0123046

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