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TGF-β1-Mediated Differentiation of Fibroblasts Is Associated with Increased Mitochondrial Content and Cellular Respiration
OBJECTIVS: Cytokine-dependent activation of fibroblasts to myofibroblasts, a key event in fibrosis, is accompanied by phenotypic changes with increased secretory and contractile properties dependent on increased energy utilization, yet changes in the energetic profile of these cells are not fully de...
Autores principales: | Negmadjanov, Ulugbek, Godic, Zarko, Rizvi, Farhan, Emelyanova, Larisa, Ross, Gracious, Richards, John, Holmuhamedov, Ekhson L., Jahangir, Arshad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388650/ https://www.ncbi.nlm.nih.gov/pubmed/25849590 http://dx.doi.org/10.1371/journal.pone.0123046 |
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