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Tissue Factor-Expressing Tumor Cells Can Bind to Immobilized Recombinant Tissue Factor Pathway Inhibitor under Static and Shear Conditions In Vitro

Mammary tumors and malignant breast cancer cell lines over-express the coagulation factor, tissue factor (TF). High expression of TF is associated with a poor prognosis in breast cancer. Tissue factor pathway inhibitor (TFPI), the endogenous inhibitor of TF, is constitutively expressed on the endoth...

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Detalles Bibliográficos
Autores principales: Che, Sara P. Y., DeLeonardis, Christine, Shuler, Michael L., Stokol, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388665/
https://www.ncbi.nlm.nih.gov/pubmed/25849335
http://dx.doi.org/10.1371/journal.pone.0123717