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Cellular Size as a Means of Tracking mTOR Activity and Cell Fate of CD4+ T Cells upon Antigen Recognition

mTOR is a central integrator of metabolic and immunological stimuli, dictating immune cell activation, proliferation and differentiation. In this study, we demonstrate that within a clonal population of activated T cells, there exist both mTOR(hi) and mTOR(lo) cells exhibiting highly divergent metab...

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Detalles Bibliográficos
Autores principales:	Pollizzi, Kristen N., Waickman, Adam T., Patel, Chirag H., Sun, Im Hong, Powell, Jonathan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388710/ https://www.ncbi.nlm.nih.gov/pubmed/25849206 http://dx.doi.org/10.1371/journal.pone.0121710

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