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Expression of CDK1(Tyr15), pCDK1(Thr161), Cyclin B1 (Total) and pCyclin B1(Ser126) in Vulvar Squamous Cell Carcinoma and Their Relations with Clinicopatological Features and Prognosis
Cyclin B1-CDK1 complex plays an important role in the regulation of cell cycle. Activation of Cyclin B1 and CDK1 and the formation of the complex in G2/M are under multiple regulations involving many regulators such as isoforms of 14-3-3 and CDC25 and Wee1. Abnormal expression of Cyclin B1 and CDK1...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388712/ https://www.ncbi.nlm.nih.gov/pubmed/25849598 http://dx.doi.org/10.1371/journal.pone.0121398 |