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In Vitro and In Vivo Metabolism and Inhibitory Activities of Vasicine, a Potent Acetylcholinesterase and Butyrylcholinesterase Inhibitor

Vasicine (VAS), a potential natural cholinesterase inhibitor, exhibited promising anticholinesterase activity in preclinical models and has been in development for treatment of Alzheimer’s disease. This study systematically investigated the in vitro and in vivo metabolism of VAS in rat using ultra p...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Shi, Xiaoyuan, Yang, Yadi, Cheng, Xuemei, Liu, Qing, Han, Han, Yang, Baohua, He, Chunyong, Wang, Yongli, Jiang, Bo, Wang, Zhengtao, Wang, Changhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388757/ https://www.ncbi.nlm.nih.gov/pubmed/25849329 http://dx.doi.org/10.1371/journal.pone.0122366

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