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In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)

PURPOSE: To study in vivo effects of the human monoclonal TSH receptor (TSHR) autoantibodies M22 (stimulating type) and K1-70 (blocking type) on thyroid hormone levels in rats. METHODS: Serum levels of total T4, free T4, M22 and K1-70 were measured following intramuscular injection of M22 IgG (2–4 μ...

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Detalles Bibliográficos
Autores principales: Furmaniak, Jadwiga, Sanders, Jane, Young, Stuart, Kabelis, Katarzyna, Sanders, Paul, Evans, Michele, Clark, Jill, Wilmot, Jane, Rees Smith, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389019/
https://www.ncbi.nlm.nih.gov/pubmed/26000124
http://dx.doi.org/10.1007/s13317-011-0025-9