Cargando…

Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences

The purpose of this study was to determine if international guidelines differ in their recommendations concerning additive therapy for advanced, but potentially curable, gastric cancer. A systematic search of the English and German literature was conducted in the databases Medline, Cochrane Database...

Descripción completa

Detalles Bibliográficos
Autores principales: Bauer, Katrin, Schroeder, Marcel, Porzsolt, Franz, Henne-Bruns, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389092/
https://www.ncbi.nlm.nih.gov/pubmed/25861518
http://dx.doi.org/10.5230/jgc.2015.15.1.10
_version_ 1782365486754824192
author Bauer, Katrin
Schroeder, Marcel
Porzsolt, Franz
Henne-Bruns, Doris
author_facet Bauer, Katrin
Schroeder, Marcel
Porzsolt, Franz
Henne-Bruns, Doris
author_sort Bauer, Katrin
collection PubMed
description The purpose of this study was to determine if international guidelines differ in their recommendations concerning additive therapy for advanced, but potentially curable, gastric cancer. A systematic search of the English and German literature was conducted in the databases Medline, Cochrane Database, Embase, and PubMed. The search terms used were 'guidelines gastric cancer,' 'guidelines stomach cancer,' and 'Leitlinien Magenkarzinom.' Six different guidelines published after January 1, 2010, in which the tumors were classified according to the seventh edition of the TNM system (2010), were identified. Although the examined guidelines were based on the same study results, their recommendations concerning accompanying therapy for gastric cancer differ considerably. While perioperative chemotherapy is recommended in Germany, Great Britain, and large parts of Europe, postoperative adjuvant radiochemotherapy or perioperative chemotherapy is recommended in the USA and Canada. In Japan, postoperative adjuvant chemotherapy is recommended.The results of identical studies were interpreted differently in different countries. Since considerable effort is required for each country to separately test relevant studies for their validity and suitability, an international cooperation could simplify the creation of a common basis for guidelines and contribute to improved comparability of international guidelines.
format Online
Article
Text
id pubmed-4389092
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Korean Gastric Cancer Association
record_format MEDLINE/PubMed
spelling pubmed-43890922015-04-08 Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences Bauer, Katrin Schroeder, Marcel Porzsolt, Franz Henne-Bruns, Doris J Gastric Cancer Review Article The purpose of this study was to determine if international guidelines differ in their recommendations concerning additive therapy for advanced, but potentially curable, gastric cancer. A systematic search of the English and German literature was conducted in the databases Medline, Cochrane Database, Embase, and PubMed. The search terms used were 'guidelines gastric cancer,' 'guidelines stomach cancer,' and 'Leitlinien Magenkarzinom.' Six different guidelines published after January 1, 2010, in which the tumors were classified according to the seventh edition of the TNM system (2010), were identified. Although the examined guidelines were based on the same study results, their recommendations concerning accompanying therapy for gastric cancer differ considerably. While perioperative chemotherapy is recommended in Germany, Great Britain, and large parts of Europe, postoperative adjuvant radiochemotherapy or perioperative chemotherapy is recommended in the USA and Canada. In Japan, postoperative adjuvant chemotherapy is recommended.The results of identical studies were interpreted differently in different countries. Since considerable effort is required for each country to separately test relevant studies for their validity and suitability, an international cooperation could simplify the creation of a common basis for guidelines and contribute to improved comparability of international guidelines. The Korean Gastric Cancer Association 2015-03 2015-03-31 /pmc/articles/PMC4389092/ /pubmed/25861518 http://dx.doi.org/10.5230/jgc.2015.15.1.10 Text en Copyright © 2015 by The Korean Gastric Cancer Association http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Bauer, Katrin
Schroeder, Marcel
Porzsolt, Franz
Henne-Bruns, Doris
Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title_full Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title_fullStr Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title_full_unstemmed Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title_short Comparison of International Guidelines on the Accompanying Therapy for Advanced Gastric Cancer: Reasons for the Differences
title_sort comparison of international guidelines on the accompanying therapy for advanced gastric cancer: reasons for the differences
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389092/
https://www.ncbi.nlm.nih.gov/pubmed/25861518
http://dx.doi.org/10.5230/jgc.2015.15.1.10
work_keys_str_mv AT bauerkatrin comparisonofinternationalguidelinesontheaccompanyingtherapyforadvancedgastriccancerreasonsforthedifferences
AT schroedermarcel comparisonofinternationalguidelinesontheaccompanyingtherapyforadvancedgastriccancerreasonsforthedifferences
AT porzsoltfranz comparisonofinternationalguidelinesontheaccompanyingtherapyforadvancedgastriccancerreasonsforthedifferences
AT hennebrunsdoris comparisonofinternationalguidelinesontheaccompanyingtherapyforadvancedgastriccancerreasonsforthedifferences